On your computer, access the folder that contains your modding software either Nexus Mod manager or Vortex for Fallout 4.Should this be the underlying cause of the mod manager issue in Fallout 4, running the mod as administrator will likely fix it. One of the reasons as to why a computer application or program including mod manager may not work as intended is because it’s only granted with limited access to system resources. First Fix: Run Mod Manager as Administrator The steps depicted in the following procedures are specifically applied to two of the most popular modding tools for Fallout 4 namely the Vortex and Nexus Mod Manager. Troubleshooting Fallout 4 Mod Manager that’s not working in Windows 10 These are the common factors that you should consider ruling out when dealing with modding issues in Fallout 4.